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- Posts: 23
- Joined: Wed Feb 06, 2019 8:59 pm
I am working on GC-MS analysis of chlorophenols with BSTFA derivatization. Recently I found the sensitivities of the chlorophenols are lower and one of them even missing. This could be due to contamination in my system (GC column DB1701). I cleaned the EI souce, replaced liner, septum, gold plate, and guard column, but this could not resolve the issue.
Someone has just suggested that the BSTFA might be the contamination source, but I have no idea about it. I am add an excess of the BSTFA (100 uL) for the derivatization as I am working on food matrix.
Does anyone here have any idea about the BSTFA thing? Thanks.