Method Re-validation?
Posted: Thu Dec 06, 2018 2:18 pm
At our last PM we had a new detector installed and our sensitivity has increased. This is causing some of our analytes to get saturated where in the past they were not.
To combat this we have increased the voltages on the problem analytes to make their ionization less efficient and prevent the saturation.
Would this change require a re-validation of the method for a clinical lab?
To combat this we have increased the voltages on the problem analytes to make their ionization less efficient and prevent the saturation.
Would this change require a re-validation of the method for a clinical lab?