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- Posts: 1
- Joined: Tue Sep 14, 2004 5:51 am
- Location: Chennai
Regarding the recovery calculation in Quantitative analysis of Drugs by LC-MS-MS, suppose our Drug is Ester and it is easily degrades to Acid in Plasma, in that case how can I calculate the recovery? I have to add both the areas of Ester and Acid or acid only? I would like to add that in the case of high concentration of Ester (drug) in plasma the degradation rate is less compared ot low concentration.
Kindly give your opinion regarding this problem
Thanks and Regards
B. Sivakumar