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Ammonium bicarbonate vs 4-Methylmorpholine as lcms buffer
Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.
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I would like to compare ammonium bicarbonaat buffer vs 4-Methylmorpholine for buffering at ph 8. Can i lower the ph of 100 mM ammonium bicarbonaat with formic acid? What acid/base do you use to adjust ph?
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The pH stability of ammonium bicarbonate buffer is not good (water must be degassed before buffer preparation). The good practise is preparation of fresh AB buffer before application.Aldijkhuizen wrote:
I would like to compare ammonium bicarbonaat buffer vs 4-Methylmorpholine for buffering at ph 8.
YesAldijkhuizen wrote:
Can i lower the ph of 100 mM ammonium bicarbonaat with formic acid?
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by he way, what acid/base do i use o adjust pH of 4-methylmorpholine?
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formic acid/ammonium hydroxideAldijkhuizen wrote:
by he way, what acid/base do i use o adjust pH of 4-methylmorpholine?
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