By Drew on Thursday, August 19, 2004 - 01:49 am:

I have observed the following when I was trying to acheive fragmentaion by LC/MS Ion Trap.

The compound I was trying to analyse gave M+H, M+NA and M+H+ACN. However, I found that l can only achieved the fragmentaion of M+H.

Please advice on whether is it possible to obtain fragmentation of M+Na and M+H+ACN by LC/MS ion trap.

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By JF on Thursday, August 19, 2004 - 04:13 am:

Increase the diclustering potential or the collision energy.

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By Bert on Thursday, August 19, 2004 - 04:30 am:

In our (ESP) experience, fragmentation of sodium adducts is most times impossible.