Low mass cut of in CID experiment

Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.

2 posts Page 1 of 1
Can any one explain why the low mass cut off in CID experiment is about 1/3 of the precursor ion? Thanking you before hand.

Well, whether you are doing scan or MS/MS on an ion trap, the low mass cutoff can usually be set by the user. I do not know the mathematical reason why 1/3 is a good value. However, I can tell you that the low mass cutoff is not a sharp boundary between stable and unstable masses. For example, m/z 100 will be transmitted more efficiently with the cutoff set to 50 rather than 60 (at least with the ion traps I've used).
2 posts Page 1 of 1

Who is online

In total there are 9 users online :: 0 registered, 0 hidden and 9 guests (based on users active over the past 5 minutes)
Most users ever online was 599 on Tue Sep 18, 2018 9:27 am

Users browsing this forum: No registered users and 9 guests

Latest Blog Posts from Separation Science

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.

Subscribe to our eNewsletter with daily, weekly or monthly updates: Food, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.

Liquid Chromatography

Gas Chromatography

Mass Spectrometry