GCMS peak integrated but no response shown

Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.

3 posts Page 1 of 1
Internal standard peak came out and integration also okay. But no response shown and retention time also shown as zero. Has anyone experienced this before? Please help! Thank you!
Geez, Samantha: tell the folks what instrument and software/version you're using, you've provided almost NOTHING.

We don't need to know what you had for lunch, etc.
Image
hard to answer a question without full information but here are some typical scenarios where most software will fail to give a response:
(1) peak area is outside the range of the calibration standards, especially if you're using a quadratic fit calibration curve
(2) you didn't run a calibration curve...
(3) processing was set to do integration but not calibration/quantification
(4) qualifier ions are too weak/not at the correct ratio, so the peak has been rejected even though the main quantifier ion looks fine
3 posts Page 1 of 1

Who is online

In total there is 1 user online :: 0 registered, 0 hidden and 1 guest (based on users active over the past 5 minutes)
Most users ever online was 1117 on Mon Jan 31, 2022 2:50 pm

Users browsing this forum: No registered users and 1 guest

Latest Blog Posts from Separation Science

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.

Subscribe to our eNewsletter with daily, weekly or monthly updates: Food & Beverage, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.

Liquid Chromatography

Gas Chromatography

Mass Spectrometry