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- Posts: 406
- Joined: Wed Jul 18, 2012 6:45 am
- Location: Germany
I don't understand the logic behind Quan/TargetLynx integration parameters. I am struggling for years and get more or less acceptable results, but I hate not having full control over the integration especially of small peaks.
Please have a look at the attached chromatogram to see what I mean.
Problem 1: Fictional baseline
https://ibb.co/B4c2rRW
Problem 2: Baseline separation or not?
https://ibb.co/hspGJjw
How can I tell the algorithms to draw the baseline of the peak not from a fictional baseline but from the actual measured data points? How to discriminate what is baseline separated and what not?
The same issues appear using "traditional" and "apex track" integration.
Many thanks in advance,
Jörg