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- Posts: 3
- Joined: Tue Jun 02, 2020 4:42 pm
I get problems with upward curvature in my calibration of PCBs since the fragmentation seems to decrease with increased concentration. If I quantitate using TIC in Chromeleon the curve becomes linear but if a use a the molecular ion as quantification ion the curve is quadratic (upward curvature). Has anyone encountered this before with this instrument. I have only used Agilent instruments (several versions of the 597x series) before and I have never seen this kind of problem before.