
 Posts: 3
 Joined: Tue Jun 12, 2018 7:09 pm
Hi Chromatography Forum.
For my bachelor's thesis, I ran competition experiments between two substrates. One has a deuterium instead of a proton (mass = 1 higher). As you can imagine, the peaks of the two substrates are basically on top of each other, so area integration gives no useful information.
I've read up on TIC and as far as I can understand, TIC sums up the intensities of each ion. So I want to know if it is possible to get the area of just a single ion fragment (i.e. m/z = 187) out of the full peak which contains ~2030 fragments?
And if so, do you know how to do it in Postrun Analysis? I've spent hours in the software and the manual, but I cannot find it...
Thank you so much in advance!
For my bachelor's thesis, I ran competition experiments between two substrates. One has a deuterium instead of a proton (mass = 1 higher). As you can imagine, the peaks of the two substrates are basically on top of each other, so area integration gives no useful information.
I've read up on TIC and as far as I can understand, TIC sums up the intensities of each ion. So I want to know if it is possible to get the area of just a single ion fragment (i.e. m/z = 187) out of the full peak which contains ~2030 fragments?
And if so, do you know how to do it in Postrun Analysis? I've spent hours in the software and the manual, but I cannot find it...
Thank you so much in advance!