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- Posts: 2
- Joined: Fri Feb 08, 2019 10:40 am
I have a problem of resolution. The test method is Organic impurities of Alcohol (USP) by GC. The resolution for system suitability requirement is NLT 1.5 between acetaldehyde and methanol but I can't achieve it without changing chromatographic conditions below.
Column: DB-624 (0.32-mm × 30-m fused-silica capillary; bonded with a 1.8-µm layer of phase G43)
split ratio: 20:1
Linear velocity: 35 cm/s
Carrier gas: Helium
Injection volume: 1.0 µL
Injection port temp: 200°C
Detector temp: 280°C
Column temp: 0-12 min : 40°C
Is there a way to improve the resolution without changing the conditions above?