Methylamine/Ethylamine/Propylamine extractions

Discussions about GC and other "gas phase" separation techniques.

10 posts Page 1 of 1
Anyone have any advice on trying to extract for Methylamine/Ethylamine/Propylamine? We currently run water samples directly and the RL's aren't very impressive. I'm hoping to extract but have been failing. I tried Hexane/THF (added salt to pull solvent out) and DCM with no success at all basically.

Anyone have any solvent/condition suggestions?
Strong cationexchange, for example oasis mcx?
What do you mean by "directly"? Is it injection of liquid water samples, or headspace?
Rndirk wrote:
What do you mean by "directly"? Is it injection of liquid water samples, or headspace?


Sorry, water directly.
Aldijkhuizen wrote:
Strong cationexchange, for example oasis mcx?

I'll have to contact them, I didn't think of trying cation exchange because of super low boiling point of Methylamine.
I would consider a headspace GC analysis
Try to add strong basics to water & hexane extraction or water & headspace.
Best regards,
Dmitriy A. Perlow
I would consider derivatizing with one of the chloroformates probably propyl and propanol for best LOD. Chloroformates work really well for amines and derivatize in aqueous solutions which can then be extracted with chloroform/isooctane and give better chromatography.
Do chloroformates work with tertiary amines? I'm specifically interested in trimethyl and triethyl amine. Do you have a link to any articles that give the details of the derivatization procedure ie solvent ratios, reaction conditions, etc?

Thanks,
Dave
no It only does primary and I think secondary. There is no room to make a carbamate on a tertiary amine.
10 posts Page 1 of 1

Who is online

In total there is 1 user online :: 0 registered, 0 hidden and 1 guest (based on users active over the past 5 minutes)
Most users ever online was 1117 on Mon Jan 31, 2022 2:50 pm

Users browsing this forum: No registered users and 1 guest

Latest Blog Posts from Separation Science

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.

Subscribe to our eNewsletter with daily, weekly or monthly updates: Food & Beverage, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.

Liquid Chromatography

Gas Chromatography

Mass Spectrometry