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- Posts: 53
- Joined: Mon Sep 26, 2011 4:02 pm
- Location: USA
Thanks for any input.
Discussions about GC and other "gas phase" separation techniques.
tom jupille wrote:
None of the integration algorithms that I know of tied to any specific peak shape. The start of the peak is usually identified when the slope of the signal exceeds a certain trigger value, and the end of the peak is identified when returns near enough to zero the values in between are summed to give the area (yes, that's a gross oversimplification, but the point is that the details of peak shape don't matter).
What CAN matter with a distorted peak is a non-linear relationship between response and analyte concentration, but as long as the entire peak stays within the linear range of the detector, the shark-fin should not have a significant impact on integration.
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