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- Posts: 148
- Joined: Wed Jul 03, 2013 1:51 am
- Location: Michigan, USA
we have to determine residual solvents (hexanol, 2-EH) in very aggresive matrices containing NaOH and organic amines at a pH of ~13. This is wrecking columns and the lab production lab is hesitant to do any sample prep other than adding base or acid to adjust pH.
We do not really need good resolution because we have obvious peaks at high S/N. Is there an old school column that is impervious to injections of caustic matrices? We only require HPLC quality plate numbers.
I have already recommended liners with wool.
Thanks...