Manual headspace method

Discussions about GC and other "gas phase" separation techniques.

2 posts Page 1 of 1
Hi all,

Just want to ask regarding some manual headspace method. I want to ask if my two compounds of interest in water have different boiling point (110degC and 300degC) in water, how am i going to set the oven temp? Because i try to put lesser volume in headspace vial due to water vapour pressure high, will cause expansion of the vial cap till loosen. I do try heat at 110degC, i able detect 110degC compound, but when not able see 300degC compound; if i heat at 180degC, the water inside become dryness, and found cap is loosen, but able detect 300degC compound, not able see 110degC compound (mayb due to loosen cap). Anyone can give advise on this?

I'd argue that headspace isn't a good option for a compound with a 300 C boiling point in a matrix with a boiling point of 100 C. Some might argue that gas chromatography isn't the best option for something with a 300 C boiling point.
2 posts Page 1 of 1

Who is online

In total there are 12 users online :: 0 registered, 0 hidden and 12 guests (based on users active over the past 5 minutes)
Most users ever online was 599 on Tue Sep 18, 2018 9:27 am

Users browsing this forum: No registered users and 12 guests

Latest Blog Posts from Separation Science

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.

Subscribe to our eNewsletter with daily, weekly or monthly updates: Food, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.

Liquid Chromatography

Gas Chromatography

Mass Spectrometry