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- Posts: 2
- Joined: Wed Oct 10, 2018 1:58 pm
I'm doing some work on a project to analyze an analyte in a cream. The problem is that the analyte is only water soluble. I was trying to use liquid liquid extraction. The cream has some water in it (~73% but we don't know the exact amount) and I was trying to use organic solvent to dissolve the cream and then allow the water layer and organic layer to separate by centrifuging, but since the analyte goes into the water layer I'm not sure how to accurately quantify without knowing the exact amount of water. Any thoughts on a better way to do this?
Just a heads up, the solubility is very limited in all organic solvents so that's what makes this really tricky.
Thanks in advance.