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- Posts: 2
- Joined: Tue May 12, 2015 3:15 pm
I am looking for a suitable internal standard and I tested corticosterone (as contains both hydroxy and carbonyl functional groups), but this did not seem to show up in the sample matrix. I tested and sugar for the TMS part and this seems to work fine and a single carbonyl containing compound and this seemed to work for the methoxyamination part, but when I try a compound that contains both functional groups it doesn't seem obivous if it has worked.
So was wandering if anyone had any experience of this reaction and suggest any alternative standards to try. Or any common compounds to look out for to test to see if the reaction is working fully.