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- Posts: 3
- Joined: Tue Nov 26, 2019 12:55 pm
Metformin is supplied as Metformin hydrochloride for solubility and I was wondering if it is possible to seperate Metformin base from the HCl by liquid liquid extraction?
pKa is 12.3, so if I raise the pH to 14, could I drive the Metformin out of the aqueous phase to seperate? Any feedback much appreciated.