What can cause decrease of column pressure over time?
Posted: Thu Nov 22, 2018 8:55 am
hi everyone,
I have been watching a decrease of column pressure over time.
It started at 11.600 psi when new, and has been slowly dropping into around 10.600 psi after almost 1000 injections.
Does this make any sense?
I'm used to see column pressure going higher, not lower.
I have introduced a "several solvent injections sequence" in the end of every sample sequences, in order to improve column cleaning at the end of the day.
It feels like column is lasting longer this way, than with just normal column wash protocols at the end of the race.
Can this might be causing increased column bleeding effect, and it might show continuous lower pressure because of it?
thanks you all for your help!
may the gods of science be with you all
I have been watching a decrease of column pressure over time.
It started at 11.600 psi when new, and has been slowly dropping into around 10.600 psi after almost 1000 injections.
Does this make any sense?
I'm used to see column pressure going higher, not lower.
I have introduced a "several solvent injections sequence" in the end of every sample sequences, in order to improve column cleaning at the end of the day.
It feels like column is lasting longer this way, than with just normal column wash protocols at the end of the race.
Can this might be causing increased column bleeding effect, and it might show continuous lower pressure because of it?
thanks you all for your help!
may the gods of science be with you all