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- Posts: 5
- Joined: Tue Oct 30, 2018 11:15 am
I am currently working on different solvent systems for VLC for plant samples. The property that I am focusing on is polarity (since this is the basis for VLC). The solvent system that is commonly used in the lab that I am working on involves hexane and ethyl acetate (polarity index of 0.0 and 4.4, respectively). I have also read that solvents with aromatic groups such as benzene and toluene are toxic, same for halogenated ones such as dichloromethane and chloroform. Other solvents are also volatile such as ethers and pet ether. I have also read on green solvents (such as Me-THF, CPME, etc) and thought of using them but I have not seen actual studies that used these for any kind of chromatography. Also, I am not sure if I can use solvents of one kind of chromatography to another, say flash chromatography solvents to VLC.
tl;dr: It's hard to look for VLC solvent systems. I wish to know what other systems I can use aside from aromatic and halogen-containing ones, and if I can also use green solvents. Lastly, can I translate one solvent system of chrom to another?
Thank you, I hope someone reads this.