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- Posts: 172
- Joined: Thu Jul 26, 2007 2:13 pm
thx
Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.
Is it possible for a 100% pure compound to produce a peak purity <100%? What could cause this? Could operating at the pKa of one of the substituent groups cause lower than expected peak purity due to the compound existing is 2 different ionized states? Is PP a useful parameter?
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