Ghost peaks with same intensity in every injection

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

17 posts Page 2 of 2
I was going to suggest using fresh MP bottles before the extensive troubleshooting. I've found this to be the cause of the majority of my ghost peak problems.
Hi all, hope someone can kindly advise me ~

I did passivation as per what was done earlier by a member here and I have narrowed down the ghost peaks to a problematic water source.

Using other source of ultra pure water from another lab, I managed to get neat blanks without any carry over peaks.

Our lab purchased a new UPW system recently from Millipore, and to my horror, the ghost peaks re-appeared again with the same intensity in every injection.

I was thinking that the water source in my lab was contaminated; but is it even possible that can happen with a new ultra pure water system?

Looking for some kind wisdom and help here.

Thanks a lot !
17 posts Page 2 of 2

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