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- Posts: 129
- Joined: Tue Dec 04, 2007 12:55 pm
- Location: China
I have two pieces of Waters e2695 HPLC, which was procured in Jan 2011. Before June 2013, we have not changed the injector syringe. In that month (June 2013), I found leakage in the syringe, so I procured new syringes from local Waters office and installed them.
The disaster happened thereafter, new syringe would leak 3-6 months after installation, we have changed 3 syringes until now. Currently, the syringes are leaking with bubbles inside, and RSD for replicate injections of standard fails from time to time.
Our test sample are basically the same as before, that mean our mobile phase and sample have not changed. So I am sure that the root cause of the leaking syringe is not the mobile phase and sample.
One Waters engineer indicates that the seal pack adjustment and compression check (we do this if the RSD is not good or leakage is suspected) may have caused damage to the syringe, which have resulted in leakage.
Do you think injector needle seal pack adjustment and compression check will cause leakage? Can you share with me any other possible causes for leaking syringe?
Thanks in advance,
Terry