problem with DMSO in RP-HPLC

[Justthisonce]

Hi everyone, I've been trying to come up with a good solvent for my analyte which has poor solubility in water. I've come across DMSO and it showed good solubility at around 25 ppm. my mobile phase was 40:60, water and acetonitrile respectively. everything was going well until the detection part. the detector showed three to four peaks close to each other, which I assume that my analyte's peak is somewhere in between. My questions are :
Is there something wrong with using DMSO as a solvent for my analyte when I'm using water: acetonitrile as the mobile phase?
or is there something wrong with the DMSO itself?
btw the analyte doesn't show good solubility in acetonitrile as well, it in fact precipitates at around 50ppm in acetonitrile.

[Consumer Products Guy]

Apparently you are not allowed to state the analyte's name.

Question: How many microliters are you injecting??? Too much "strong"/organic in the injection solvent is bad. Try smaller injection volumes, see if anything changes.

[Justthisonce]

Apparently you are not allowed to state the analyte's name.

Question: How many microliters are you injecting??? Too much "strong"/organic in the injection solvent is bad. Try smaller injection volumes, see if anything changes.

So far my injection volume has been 20 microliters. I'll try smaller volumes next time! Thanks for the reply.