bull0121 wrote:
Hi everyone,
I am looking at different HPLC columns from Agilent, Waters, Phenomenex and Thermo. Do you guys have any preference on vendors when selecting small molecule analytical columns or UPLC columns? Is lifespan, sensitivity, resolution better between vendors?
Thanks!
In my experience, columns from the big vendors are going to be very similar. Preference usually comes down to previous working relationships/use, vendor contracts, pricing deals, and recommendations from colleagues who are performing the same or close to the same method as you.
If your lab doesn't have a vendor preference, I'd ask someone performing the same analyses as you, and also see what columns are referenced in relevant literature.
As my mama told me, "you better shop around."