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- Posts: 5
- Joined: Fri Jun 25, 2021 4:03 pm
I have already experimented with HBF4 as an additive in my LC system and have had great success with it. The pH is adjusted to 2 and I get great separation for my compounds (preparative HPLC).
Now I was wondering if its possible to use nitric acid (HNO3) as an eluent additive and not damage the system? I know that it is corrosive but so is HBF4 and I havent experienced any signs of degradation so far.
I know its VERY unusual but in my case it is essential to use this uncommon acids.