I see someone resurrected an old post from 2016, though the confusion still exists today. Let us act like knowledgeable scientists, not sales people, and use the correct name, "
HPLC".
Recap:
"UPLC" is a Waters trademark only. The technique used is HPLC.
"LC" is NOT HPLC. "LC" is a very generic term for liquid chromatography.
"UHPLC" and "UPLC" were developed as marketing terms only. They are not scientific terms for the technique. The technique is HPLC. As scientists, we should not use marketing names, esp when their is a correct name available. It is "HPLC". Just because you change the packing material, but still run under high pressure conditions makes it HPLC, always... Fully porous, superficially porous, monolithic, irregular, spherical, 1.7 u, 2 u, 5 u, 10u, 20u particles are all types of HPLC supports.
My boss mentioned that back in the 1980's (and 90's to present day), they used lots of different column types and supports; very narrow ID silica tubing, 1 mm ID column, 2 mm ID columns with 3 and 5 micron particles on HPLC systems, some running as high as 100,000 psi !!!! It was always referred to as HPLC. No extra marketing names were needed. Those that are new to the field may not know these things, but the name of HPLC still applies and there is no scientific reason to use silly names such as 'UHPLC' (which is HPLC) for an analytical technique that already has an accurate name. Column details are part of the HPLC method.
Sales people love making up names to make it appear they have a new product to sell (they get paid to do so!). We know better.
More info:
"
Terminology. Which is it? UPLC, UHPLC or HPLC? The correct name is still HPLC";
https://hplctips.blogspot.com/2015/08/t ... lc-or.html