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- Posts: 5
- Joined: Tue Oct 30, 2018 11:15 am
Are there models, or perhaps studies, that can help me optimize the solvent systems I am going to use in TLC? Preferably one that involves solvent polarity.
I read about the PRISMA system by Sz. Nyiredy and I thought I was already doing a binary solvent system with my hexane-ethyl acetate optimization (replacing the polar and nonpolar components), but I just realized that hexane is not considered a "solvent" but a diluent due to its near-zero solvent strength, therefore I cannot do the model as one of its functions involve solvent strength.