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- Posts: 1107
- Joined: Wed Dec 22, 2010 10:17 pm
- Location: Chicago
I don't have an LC/MS. I have a GC/MS and have read the apps about the older FDA method. Extract with water/ACN/diethylamine cent/filt, evap and silylate.
I am looking to replace the silylation with chlororformate derivatization either propyl or isobutyl. I just wish it were possible not to use diethlamine as it will have to be evaporated first or it will use up all the chloroformate. I understand the diethylamine breaks up complexes of melamine. Is there a nonamine alternative? I'm surprised noone has made a chloroformate paper on melamine as it works very well on amines.