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- Posts: 104
- Joined: Tue Aug 04, 2015 9:57 pm
We are experiencing a baseline dip directly after our peak of interest that is about 4X noise. It does not seem to be effected by the size of the peak of interest itself.
The analysis is for inositol utilizing an RI detector under conditions that are fairly close to the USP monograph for this compound.
Agilent had us do an extended rinse of the reference cell and this did not help. I was wondering if there are some general possible reasons for this phenomenon when working with an RI detector that others have come across.
Thanks