-
- Posts: 406
- Joined: Wed Jul 18, 2012 6:45 am
- Location: Germany
This picture shows a pressure profile of some isocratic runs (90 % MeOH/10 % water) on an Acquity H-class QSM, detector is a Xevo TQ-S. In my understanding, all injections should have the same operating pressure, not?
Retention time is stable (+-0.02 min) and so is peak area (+- 1 %). Anyway I'd like to understand what is causing this dramatic pressure differences from run to run.
Any ideas?
Regards
Jörg